Title : Impact of RUNX2 gene silencing on the gemcitabine sensitivity of p53‑mutated pancreatic cancer MiaPaCa‑2 spheres.

Pub. Date : 2018 Jun

PMID : 29620279






3 Functional Relationships(s)
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1 Impact of RUNX2 gene silencing on the gemcitabine sensitivity of p53-mutated pancreatic cancer MiaPaCa-2 spheres. gemcitabine tumor protein p53 Homo sapiens
2 In the present study, we have demonstrated that, similar to the conventional 2D monolayer culture systems which often lack in vivo physiological insights, RUNX2 gene silencing increases the gemcitabine (GEM) sensitivity of the 3D spheres generated from p53-mutated pancreatic cancer MiaPaCa-2 cells. gemcitabine tumor protein p53 Homo sapiens
3 In the present study, we have demonstrated that, similar to the conventional 2D monolayer culture systems which often lack in vivo physiological insights, RUNX2 gene silencing increases the gemcitabine (GEM) sensitivity of the 3D spheres generated from p53-mutated pancreatic cancer MiaPaCa-2 cells. gemcitabine tumor protein p53 Homo sapiens