Title : Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment.

Pub. Date : 2018 Jun

PMID : 29620255






2 Functional Relationships(s)
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1 The region encompassing the overlapping genes ERCC1, CD3EAP and PPP1R13L may be involved in linking the upstream and downstream genes, while the different splicing isoforms of ERCC1 affect the expression of its overlapping genes, suggesting potential application in cisplatin resistance in NSCLC treatment. Cisplatin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens
2 The region encompassing the overlapping genes ERCC1, CD3EAP and PPP1R13L may be involved in linking the upstream and downstream genes, while the different splicing isoforms of ERCC1 affect the expression of its overlapping genes, suggesting potential application in cisplatin resistance in NSCLC treatment. Cisplatin ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens