Title : Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells.

Pub. Date : 2018 Apr 3

PMID : 29615666






2 Functional Relationships(s)
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1 Notably, significant upregulation of genes involved in unsaturated fatty acid metabolism [stearoyl-CoA desaturase (SCD)] and cholesterol biosynthesis [3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)], were associated with atorvastatin insensitivity. Fatty Acids, Unsaturated 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 Notably, significant upregulation of genes involved in unsaturated fatty acid metabolism [stearoyl-CoA desaturase (SCD)] and cholesterol biosynthesis [3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)], were associated with atorvastatin insensitivity. Fatty Acids, Unsaturated 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens