Pub. Date : 1988 Jan
PMID : 2961554
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High affinity insulin-like growth factor I (IGF-I) receptors are expressed by two human neural derived cell lines, SK-N-SH and SK-N-MC. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |
| 2 | High affinity insulin-like growth factor I (IGF-I) receptors are expressed by two human neural derived cell lines, SK-N-SH and SK-N-MC. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |
| 3 | Specific [125I]IGF-I binding to crude membranes was 23.4% for SK-N-SH and 10.7% for SK-N-MC, with 50% inhibition of binding by unlabeled IGF-I between 0.6-0.7 nM. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |
| 4 | The IGF-I receptor alpha-subunits of SK-N-SH have an apparent Mr of 126K, whereas that for SK-N-MC is 132K. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |
| 5 | Furthermore, IGF-I stimulated iododeoxyuridine uptake in both SK-N-SH and SK-N-MC in a dose-dependent manner, suggesting that these cells may be used to study the role of IGF-I action on neural tissues. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |
| 6 | Furthermore, IGF-I stimulated iododeoxyuridine uptake in both SK-N-SH and SK-N-MC in a dose-dependent manner, suggesting that these cells may be used to study the role of IGF-I action on neural tissues. | sk-n-sh | insulin like growth factor 1 | Homo sapiens |