Pub. Date : 2018
PMID : 29613828
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TNF-alpha induced mitochondrial dysfunction with impaired basal, ATP-linked, and maximal respiration, decreased cellular ATP synthesis, and increased mitochondrial superoxide production (measured by MitoSOX red fluorescence), which were rescued by inhibiting HDACs with MPT0E014 (1 muM, a Class I and IIb inhibitor), or MS-275 (1 muM, a Class I inhibitor). | Superoxides | tumor necrosis factor | Homo sapiens |