Pub. Date : 2018 Jul
PMID : 29608917
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Chronic hyper-reflexia induced by GlyT2-ASO treatment was effectively blocked by intrathecal glycine. | Glycine | solute carrier family 6 member 5 | Rattus norvegicus |
2 | These data demonstrate that spinal GlyT2 downregulation provides only a time-limited therapeutic benefit and that subsequent loss of glycine vesicular synthesis resulting from chronic GlyT2 downregulation near completely eliminates the tonic glycine-ergic activity and is functionally expressed as profound spinal hyper-reflexia. | Glycine | solute carrier family 6 member 5 | Rattus norvegicus |
3 | These data demonstrate that spinal GlyT2 downregulation provides only a time-limited therapeutic benefit and that subsequent loss of glycine vesicular synthesis resulting from chronic GlyT2 downregulation near completely eliminates the tonic glycine-ergic activity and is functionally expressed as profound spinal hyper-reflexia. | Glycine | solute carrier family 6 member 5 | Rattus norvegicus |