Title : Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol.

Pub. Date : 2018 Jun

PMID : 29602797






1 Functional Relationships(s)
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1 Mass spectral analysis of CYP2J2 partially inactivated by EE showed two distinct protein masses in the deconvoluted spectrum that exhibited a mass difference of approximately 312 Da, which is equivalent to the sum of the mass of EE and one oxygen atom. Oxygen cytochrome P450 family 2 subfamily J member 2 Homo sapiens