Title : Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury.

Pub. Date : 2018 May

PMID : 29599139






7 Functional Relationships(s)
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Protein Name
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1 Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury. Dinoprostone prostaglandin E synthase Mus musculus
2 Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury. Dinoprostone prostaglandin E synthase Mus musculus
3 Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury. Dinoprostone prostaglandin E synthase Mus musculus
4 Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE2 (Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury. Dinoprostone prostaglandin E synthase Mus musculus
5 To examine the role of mPGES-1-derived PGE2 (prostaglandin E2) in vascular remodeling without the IP. Dinoprostone prostaglandin E synthase Mus musculus
6 To examine the role of mPGES-1-derived PGE2 (prostaglandin E2) in vascular remodeling without the IP. Dinoprostone prostaglandin E synthase Mus musculus
7 CONCLUSIONS: Removal of the IP receptors unmasks a protective role of mPGES-1-derived PGE2 in limiting injury-induced vascular hyperplasia. Dinoprostone prostaglandin E synthase Mus musculus