Title : [Mechanism of α-lipoic acid promoting iron efflux in substantia nigra cells of Parkinson's disease rats].

Pub. Date : 2018 Jan

PMID : 29595455






1 Functional Relationships(s)
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1 Objective To observe the effect of alpha-lipoic acid (alpha-LA) on the expressions of iron regulatory protein 2 (IRP2) and ferroportin1 (FP1) in substantia nigra of rats with Parkinson"s disease (PD) and explore the mechanism by which alpha-LA regulates iron efflux in substantia nigra cells of PD rat models. Iron iron responsive element binding protein 2 Rattus norvegicus