Title : Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.

Pub. Date : 2018 Mar 27

PMID : 29587720






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1 Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review. Metyrapone proopiomelanocortin Homo sapiens
2 Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review. Metyrapone proopiomelanocortin Homo sapiens
3 Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review. Metyrapone proopiomelanocortin Homo sapiens
4 We presented a case of EAS in which ACTH production by a lung tumour was reduced by metyrapone (MTP) and also reviewed previous cases of ectopic ACTH production suppressed via steroidogenesis inhibition. Metyrapone proopiomelanocortin Homo sapiens
5 We presented a case of EAS in which ACTH production by a lung tumour was reduced by metyrapone (MTP) and also reviewed previous cases of ectopic ACTH production suppressed via steroidogenesis inhibition. Metyrapone proopiomelanocortin Homo sapiens
6 ACTH levels and cortisol and UFC levels were normalised and the ACTH-producing lung tumour was ablated after MTP treatment. Metyrapone proopiomelanocortin Homo sapiens
7 The patients were treated with ketoconazole (KTZ) and/or MTP and exhibited ACTH and cortisol/UFC suppression, but tumour regression was observed only in our case. Metyrapone proopiomelanocortin Homo sapiens
8 CONCLUSION: MTP and/or KTZ may reduce ACTH and cortisol production. Metyrapone proopiomelanocortin Homo sapiens