Title : Smad7 deficiency decreases iron and haemoglobin through hepcidin up-regulation by multilayer compensatory mechanisms.

Pub. Date : 2018 Jun

PMID : 29575577






1 Functional Relationships(s)
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1 To maintain iron homoeostasis, the iron regulatory hormone hepcidin is tightly controlled by BMP-Smad signalling pathway, but the physiological role of Smad7 in hepcidin regulation remains elusive. Iron hepcidin antimicrobial peptide Mus musculus