Pub. Date : 2018 Mar 22
PMID : 29565268
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis. | beta-thujaplicin | matrix metallopeptidase 2 | Homo sapiens |
| 2 | An observed increase in protein expression of matrix metalloproteinases (MMPs) -2/-9 in A549 cells was significantly inhibited by hinokitiol. | beta-thujaplicin | matrix metallopeptidase 2 | Homo sapiens |
| 3 | These observations indicate that hinokitiol inhibited the migration of lung cancer A549 cells through several mechanisms, including the activation of caspases-9 and -3, induction of p53/Bax and antioxidant CAT and SOD, and reduction of MMP-2 and -9 activities. | beta-thujaplicin | matrix metallopeptidase 2 | Homo sapiens |