Title : Elevated monoamine oxidase A activity and protein levels in rodent brain during acute withdrawal after chronic intermittent ethanol vapor exposure.

Pub. Date : 2018 Apr 1

PMID : 29549852






6 Functional Relationships(s)
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1 Elevations in MAO-A level, especially in the prefrontal and anterior cingulate cortex (PFC and ACC), are associated with low mood states, including the dysphoria of early alcohol withdrawal in humans. Alcohols monoamine oxidase A Homo sapiens
2 The aim of the present study was to determine whether chronic alcohol vapor exposure causes an upregulation of MAO-A activity or level in the PFC and ACC of rodents during acute withdrawal. Alcohols monoamine oxidase A Homo sapiens
3 CONCLUSIONS: The results of this study suggest a causal relationship between acute alcohol withdrawal and elevated MAO-A levels and activity, clarifying the observation of greater MAO-A binding in human alcohol withdrawal. Alcohols monoamine oxidase A Homo sapiens
4 CONCLUSIONS: The results of this study suggest a causal relationship between acute alcohol withdrawal and elevated MAO-A levels and activity, clarifying the observation of greater MAO-A binding in human alcohol withdrawal. Alcohols monoamine oxidase A Homo sapiens
5 CONCLUSIONS: The results of this study suggest a causal relationship between acute alcohol withdrawal and elevated MAO-A levels and activity, clarifying the observation of greater MAO-A binding in human alcohol withdrawal. Alcohols monoamine oxidase A Homo sapiens
6 CONCLUSIONS: The results of this study suggest a causal relationship between acute alcohol withdrawal and elevated MAO-A levels and activity, clarifying the observation of greater MAO-A binding in human alcohol withdrawal. Alcohols monoamine oxidase A Homo sapiens