Title : NF-κB-driven improvement of EHD1 contributes to erlotinib resistance in EGFR-mutant lung cancers.

Pub. Date : 2018 Apr 1

PMID : 29549343






1 Functional Relationships(s)
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1 Moreover, we demonstrated that miR-590 targeted the 3"-UTR of EHD1 and was regulated by NK-kappaB, resulting in downregulated EHD1 expression, increased erlotinib sensitivity and repressed NSCLC cancer stem-like properties in vitro and in vivo. Erlotinib Hydrochloride microRNA 590 Homo sapiens