Pub. Date : 2018 Apr
PMID : 29541457
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ristocetin induces phosphorylated-HSP27 (HSPB1) release from the platelets of type 2 DM patients: Anti-platelet agent-effect on the release. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 2 | Ristocetin induces phosphorylated-HSP27 (HSPB1) release from the platelets of type 2 DM patients: Anti-platelet agent-effect on the release. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 3 | In the present study, we investigated the effect of ristocetin, a glycoprotein (GP)Ib/IX/V activator, on the release of HSP27 and the effect of anti-platelet agents, such as acetylsalicylic acid (ASA), on this release. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 4 | On the other hand, the levels of phosphorylated-HSP27 induced by ristocetin in the platelets from a patient of the anti-platelet group taking ASA were significantly lower than those from a patient of the control group. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 5 | The levels of HSP27 release from the ristocetin-stimulated platelets were significantly correlated with the levels of phosphorylated-HSP27 in the platelets from patients in the two groups. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 6 | The levels of HSP27 release from the ristocetin-stimulated platelets were significantly correlated with the levels of phosphorylated-HSP27 in the platelets from patients in the two groups. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |
| 7 | These results strongly suggest that anti-platelet agents inhibit the HSP27 release from platelets stimulated by ristocetin but not the aggregation in type 2 DM patients. | Ristocetin | heat shock protein family B (small) member 1 | Homo sapiens |