Title : Tumor-promoting cyanotoxin microcystin-LR does not induce procarcinogenic events in adult human liver stem cells.

Pub. Date : 2018 Apr 15

PMID : 29534881






1 Functional Relationships(s)
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1 Cellular accumulation of MC-LR occurred most likely via mechanisms independent on organic anion transporting polypeptides (OATPs) or multidrug resistance (MDR) proteins, as indicated (a) by a gene expression analysis of 11 human OATP genes and 4 major MDR genes (MDR1/P-glycoprotein, MRP1, MRP2 and BCRP); (b) by non-significant effects of OATP or MDR1 inhibitors on MC-LR uptake. cyanoginosin LR CD9 molecule Homo sapiens