Title : Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss.

Pub. Date : 2018 May 1

PMID : 29529199






1 Functional Relationships(s)
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1 In this study we explored the hypothesis that superoxide anions participate in the generation of the Parkin and PINK1 associated phenotypic effect by testing the capacity of endogenous and exogenous superoxide dismutating molecules to rescue the toxic effects induced by loss of PINK1 or Parkin, in both cellular and fly models. Superoxides PTEN-induced putative kinase 1 Drosophila melanogaster