Title : Arsenite increases Cyclin D1 expression through coordinated regulation of the Ca2+/NFAT2 and NF-κB pathways via ERK/MAPK in a human uroepithelial cell line.

Pub. Date : 2018 Mar 1

PMID : 29528074






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Arsenite increases Cyclin D1 expression through coordinated regulation of the Ca2+/NFAT2 and NF-kappaB pathways via ERK/MAPK in a human uroepithelial cell line. arsenite cyclin D1 Homo sapiens
2 Cyclin D1 is known as a proto-oncogene and the level of this protein was increased in SV-HUC-1 cells treated with arsenite for 24 h and long-term. arsenite cyclin D1 Homo sapiens
3 The results suggest that regulation of Cyclin D1 protein expression by arsenite in SV-HUC-1 cells is dependent on ERK/NFAT2 and ERK/NF-kappaB, but is not dependent on JNK or p38. arsenite cyclin D1 Homo sapiens