Title : Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases.

Pub. Date : 2018

PMID : 29527530

1 Functional Relationships(s)
Compound Name
Protein Name
1 Oxyimino-cephalosporins, such as cefotaxime and ceftazidime, however, are poor substrates for TEM-1 and were introduced, in part, to circumvent beta-lactamase-mediated resistance. Cefotaxime CD248 molecule Homo sapiens