Pub. Date : 2018 Feb 9
PMID : 29515788
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CD44 exerts a functional role during EMT induction in cisplatin-resistant head and neck cancer cells. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |
| 2 | The present study reports that oral cancer cells switch from expressing the CD44 variant form (CD44v) to expressing the standard form (CD44s) during acquisition of cisplatin-resistance, which resulted in EMT induction. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |
| 3 | CD44s induced an EMT phenotype in cisplatin resistant cells by up-regulating ZEB1, a transcriptional repressor of E-cadherin. | Cisplatin | CD44 molecule (Indian blood group) | Homo sapiens |