Pub. Date : 2018
PMID : 29487526
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, the knockdown of MIAT significantly sensitized PC9 and gefitinib-resistant PC9 cells to gefitinib in vitro and in vivo, and increased the expression of miR-34a and inactivated PI3K/Akt signaling. | Gefitinib | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Taken together, our findings demonstrated that knockdown of MIAT by siRNA enhances lung cancer cells to gefitinib through the PI3K/Akt signaling pathway by epigenetically regulating miR-34a. | Gefitinib | AKT serine/threonine kinase 1 | Homo sapiens |