Pub. Date : 2018 Feb 22
PMID : 29472524
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib. | Sorafenib | autophagy related 16 like 1 | Homo sapiens |
| 2 | Our findings show that targeting the PU.1-miR-142-3p-ATG5/ATG16L1 axis may be a useful therapeutic strategy for preventing cyto-protective autophagy to overcome sorafenib resistance. | Sorafenib | autophagy related 16 like 1 | Homo sapiens |