Title : A Genetic Screen for Investigating the Human Lysosomal CystineTransporter, Cystinosin.

Pub. Date : 2018 Feb 21

PMID : 29467429






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cystinosin, a lysosomal transporter is involved in the efflux of cystine from the lysosome to the cytosol. Cystine cystinosin, lysosomal cystine transporter Homo sapiens
2 We show that human cystinosin expressed in this yeast confers growth on cystine when the protein is mistargeted to the plasma membrane by the deletion of the C-terminal targeting signal, GYQDL. Cystine cystinosin, lysosomal cystine transporter Homo sapiens