Title : miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg).

Pub. Date : 2018 Feb 19

PMID : 29459719






4 Functional Relationships(s)
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1 miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg). mir-142-3p autophagy related 16 like 1 Homo sapiens
2 We demonstrate that miR-142-3p downregulates ATG16L1 mRNA and production of ATG16L1, that has been linked to autoimmune diseases. mir-142-3p autophagy related 16 like 1 Homo sapiens
3 We demonstrate that miR-142-3p downregulates ATG16L1 mRNA and production of ATG16L1, that has been linked to autoimmune diseases. mir-142-3p autophagy related 16 like 1 Homo sapiens
4 In aggregate, these studies provide a new approach that uses miR-142-3p knockdown to increase tTreg cell efficacy by increasing ATG16L1 mRNA and protein and the autophagy process. mir-142-3p autophagy related 16 like 1 Homo sapiens