Pub. Date : 2018 Feb 19
PMID : 29459719
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg). | mir-142-3p | autophagy related 16 like 1 | Homo sapiens |
2 | We demonstrate that miR-142-3p downregulates ATG16L1 mRNA and production of ATG16L1, that has been linked to autoimmune diseases. | mir-142-3p | autophagy related 16 like 1 | Homo sapiens |
3 | We demonstrate that miR-142-3p downregulates ATG16L1 mRNA and production of ATG16L1, that has been linked to autoimmune diseases. | mir-142-3p | autophagy related 16 like 1 | Homo sapiens |
4 | In aggregate, these studies provide a new approach that uses miR-142-3p knockdown to increase tTreg cell efficacy by increasing ATG16L1 mRNA and protein and the autophagy process. | mir-142-3p | autophagy related 16 like 1 | Homo sapiens |