Title : Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation.

Pub. Date : 2018 Mar

PMID : 29444596






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1 Importantly, our results display interleukin-1betatreatment significantly increased the expressions of senescence genes (caveolin-1, PAI-1 and p21), which were prevented by agonist arachidonyl-2-chloroethylamide treatment. arachidonyl-2-chloroethylamide H3 histone pseudogene 16 Homo sapiens