Title : Activation of the cannabinoid receptor 1 by ACEA suppresses senescence in human primary chondrocytes through sirt1 activation.

Pub. Date : 2018 Mar

PMID : 29444596






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1 These findings suggest that activation of cannabinoid receptor 1 by agonist arachidonyl-2-chloroethylamide might have a protective effect against pro-inflammatory cytokines such as interleukin-1beta-induced chondrocytes senescence in osteoarthritis patients. arachidonyl-2-chloroethylamide interleukin 1 beta Homo sapiens