Pub. Date : 2018
PMID : 29441065
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Adipocyte Fatty Acid-Binding Protein Promotes Palmitate-Induced Mitochondrial Dysfunction and Apoptosis in Macrophages. | Palmitates | fatty acid binding protein 4 | Homo sapiens |
2 | PA treatment upregulated the expression of adipocyte fatty acid-binding protein (A-FABP), a critical regulator of fatty acid trafficking and lipid metabolism. | Palmitates | fatty acid binding protein 4 | Homo sapiens |
3 | PA treatment upregulated the expression of adipocyte fatty acid-binding protein (A-FABP), a critical regulator of fatty acid trafficking and lipid metabolism. | Palmitates | fatty acid binding protein 4 | Homo sapiens |
4 | Thus, this study suggested that PA-mediated macrophage apoptosis through A-FABP upregulation, which subsequently resulted in mitochondrial dysfunction and reactive oxidative stress. | Palmitates | fatty acid binding protein 4 | Homo sapiens |