Title : Adipocyte Fatty Acid-Binding Protein Promotes Palmitate-Induced Mitochondrial Dysfunction and Apoptosis in Macrophages.

Pub. Date : 2018

PMID : 29441065






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Adipocyte Fatty Acid-Binding Protein Promotes Palmitate-Induced Mitochondrial Dysfunction and Apoptosis in Macrophages. Palmitates fatty acid binding protein 4 Homo sapiens
2 PA treatment upregulated the expression of adipocyte fatty acid-binding protein (A-FABP), a critical regulator of fatty acid trafficking and lipid metabolism. Palmitates fatty acid binding protein 4 Homo sapiens
3 PA treatment upregulated the expression of adipocyte fatty acid-binding protein (A-FABP), a critical regulator of fatty acid trafficking and lipid metabolism. Palmitates fatty acid binding protein 4 Homo sapiens
4 Thus, this study suggested that PA-mediated macrophage apoptosis through A-FABP upregulation, which subsequently resulted in mitochondrial dysfunction and reactive oxidative stress. Palmitates fatty acid binding protein 4 Homo sapiens