Title : Leptospira interrogans infection leads to IL-1β and IL-18 secretion from a human macrophage cell line through reactive oxygen species and cathepsin B mediated-NLRP3 inflammasome activation.

Pub. Date : 2018 Apr

PMID : 29432801






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, the levels of IL-1beta and IL-18 production decreased in CA-074 (a cathepsin B inhibitor) and NAC (an anti-oxidant) pretreated human macrophages, compared to untreated controls. N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline cathepsin B Homo sapiens