Title : STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells.

Pub. Date : 2018 Mar 1

PMID : 29431732






1 Functional Relationships(s)
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1 Specifically, blocking AhR redirected IFN-beta signaling to STAT3 phosphorylation through both tyrosine and serine sites, which subsequently facilitated STAT3 nuclear translocation and subsequent binding to the p53 promoter in the nucleus. Tyrosine tumor protein p53 Homo sapiens