Pub. Date : 2018 Oct 15
PMID : 29428397
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene. | Raloxifene Hydrochloride | protein tyrosine kinase 2 beta | Homo sapiens |
| 2 | In addition we found that Pyk2-KO OBs cultured in the presence of either 17beta-estradiol (E2) or raloxifene, a SERM used for the treatment of post-menopausal osteoporosis, showed a further robust increase in alkaline phosphatase (ALP) activity and mineralization. | Raloxifene Hydrochloride | protein tyrosine kinase 2 beta | Homo sapiens |