Title : OTUD7B upregulation predicts a poor response to paclitaxel in patients with triple-negative breast cancer.

Pub. Date : 2018 Jan 2

PMID : 29416635






1 Functional Relationships(s)
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1 In silico analysis suggested that OTUD7B regulation, probably owing to miR-1180 downregulation, may negatively regulate the NF-kappaB-Lin28 axis which in turn triggers Let-7 microRNA-mediated caspase-3 downregulation, thereby conferring paclitaxel resistance in TNBCs. Paclitaxel caspase 3 Homo sapiens