Title : Activation of autophagy is required for Oroxylin A to alleviate carbon tetrachloride-induced liver fibrosis and hepatic stellate cell activation.

Pub. Date : 2018 Mar

PMID : 29414645






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Attractively, Oroxylin A treatment also markedly up-regulated the expression of autophagy makers, LC3-B, Atg3, Atg4, Atg5, Beclin1/Atg6, Atg7, Atg9, ATG12, and Atg14, and apparently reduced the expression of autophagy substrate p62 in both CCl4-induced murine model of liver fibrosis and PDGF-BB-treated HSCs. 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one autophagy related 12 Mus musculus