Pub. Date : 2018 Feb 6
PMID : 29410428
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that this conserved protein (PF3D7_0629500 in Plasmodium falciparum; AAT1 in P. chabaudi) is a structural homologue of the yeast amino acid transporter Tat2p, which is known to mediate quinine uptake and toxicity. | Quinine | aromatic amino acid transmembrane transporter TAT2 | Saccharomyces cerevisiae S288C |
| 2 | Like Tat2p, PF3D7_0629500-dependent quinine hypersensitivity was suppressible with tryptophan, consistent with a common transport mechanism. | Quinine | aromatic amino acid transmembrane transporter TAT2 | Saccharomyces cerevisiae S288C |