Pub. Date : 2018 Apr
PMID : 29393493
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of MUS81 improves the chemical sensitivity of olaparib by regulating MCM2 in epithelial ovarian cancer. | olaparib | MUS81 structure-specific endonuclease subunit | Homo sapiens |
| 2 | The sensitivity of MUS81 to olaparib was investigated by cell proliferation, colony formation assays and flow cytometry. | olaparib | MUS81 structure-specific endonuclease subunit | Homo sapiens |
| 3 | Moreover, downregulation of MUS81 increased the sensitivity of EOC cells to olaparib by inducing S phase arrest and promoting apoptosis through activation of MCM2. | olaparib | MUS81 structure-specific endonuclease subunit | Homo sapiens |