Title : Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8.

Pub. Date : 2018 Jul

PMID : 29384270






3 Functional Relationships(s)
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1 Cognitive deficits and increases in creatine precursors in a brain-specific knockout of the creatine transporter gene Slc6a8. Creatine solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Mus musculus
2 Slc6a8-/y mice lacked whole body Cr and exhibited cognitive deficits. Creatine solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Mus musculus
3 The results show that the loss of cerebral Cr is responsible for the learning and memory deficits seen in ubiquitous Slc6a8-/y mice. Creatine solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Mus musculus