Title : Lactate increases myotube diameter via activation of MEK/ERK pathway in C2C12 cells.

Pub. Date : 2018 Jun

PMID : 29377587






2 Functional Relationships(s)
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1 MEK inhibitor U0126 depressed the phosphorylation of ERK-p90RSK and increase in myotube diameter induced by lactate. Lactic Acid midkine Mus musculus
2 CONCLUSION: These observations suggest that lactate-associated increase in the diameter of C2C12 myotubes is induced via activation of GRP81-mediated MEK/ERK pathway. Lactic Acid midkine Mus musculus