Title : A Natural Benzofuran from the Patagonic Aleurodiscus vitellinus Fungus has Potent Neuroprotective Properties on a Cellular Model of Amyloid-β Peptide Toxicity.

Pub. Date : 2018

PMID : 29376877






3 Functional Relationships(s)
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Protein Name
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1 Compounds containing a benzofuran ring have been described to play an important role in decreasing Abeta-induced toxicity; however, only synthetic benzofurans have been tested thus far. benzofuran amyloid beta precursor protein Rattus norvegicus
2 The results suggest a potent neuroprotective effect of this naturally occurring benzofuran against Abeta peptide toxicity that could be mediated by an interference with it binding to plasma membrane, and lead Fx as new chemical entity to develop pharmacological tools against Abeta peptide neurotoxicity. benzofuran amyloid beta precursor protein Rattus norvegicus
3 The results suggest a potent neuroprotective effect of this naturally occurring benzofuran against Abeta peptide toxicity that could be mediated by an interference with it binding to plasma membrane, and lead Fx as new chemical entity to develop pharmacological tools against Abeta peptide neurotoxicity. benzofuran amyloid beta precursor protein Rattus norvegicus