Title : Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages.

Pub. Date : 2018 Jan 26

PMID : 29374208






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Gbp1 knockdown (Kd) macrophages have impaired mitochondrial respiratory function, which is further supported by down-regulation of genes encoding electron transport chain components and genes involved in fatty acid oxidation and mitochondrial function. Fatty Acids guanylate binding protein 2b Mus musculus