Pub. Date : 2017
PMID : 29369297
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 agonist and many different administration routes are available for different mechanisms and different effects. | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 2 | Resiniferatoxin (RTX) is an ultrapotent synthetic TRPV1 agonist and many different administration routes are available for different mechanisms and different effects. | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 3 | Additionally, we evaluated the expression of TRPV1 in dorsal root ganglia (DRG) by western blotting after PRE- and POST-treatment with RTX. | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 4 | CONCLUSION: The presented data demonstrated that both PRE- and POST-treatment with RTX given intrathecally produced potent antiallodynic activities in CCI mice and that POST-treatment can reduce TRPV1 expression in DRG, suggesting that POST-treatment RTX can revert central sensitization and its associated allodynia. | resiniferatoxin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |