Title : Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.

Pub. Date : 2018 Apr 1

PMID : 29363544






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Targeting IRAK4 or IL1beta rendered PDAC tumors less fibrotic and more sensitive to gemcitabine. gemcitabine interleukin 1 beta Homo sapiens