Title : Target engagement and histopathology of neuraxial resiniferatoxin in dog.

Pub. Date : 2018 Mar

PMID : 29361418






2 Functional Relationships(s)
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1 OBJECTIVE: To evaluate target engagement of intracisternally (IC) delivered TRPV1 agonist, resiniferatoxin (RTX), as measured by primary afferent and dorsal horn substance P immunoreactivity (sP-IR), histopathology and thermal escape latencies in dogs. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Canis lupus familiaris
2 OBJECTIVE: To evaluate target engagement of intracisternally (IC) delivered TRPV1 agonist, resiniferatoxin (RTX), as measured by primary afferent and dorsal horn substance P immunoreactivity (sP-IR), histopathology and thermal escape latencies in dogs. resiniferatoxin transient receptor potential cation channel subfamily V member 1 Canis lupus familiaris