Title : Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells.

Pub. Date : 2018 Jan 23

PMID : 29360760






2 Functional Relationships(s)
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1 Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells. Berberine AKT serine/threonine kinase 1 Homo sapiens
2 In conclusion, BBR promotes the expression of CDKIs p21Cip1 and p27Kip1 via regulating the Akt/FoxO3a/Skp2 axis and further induces HCC G0/G1 phase cell cycle arrest. Berberine AKT serine/threonine kinase 1 Homo sapiens