Title : A mathematical model of the mevalonate cholesterol biosynthesis pathway.

Pub. Date : 2018 Apr 14

PMID : 29355536






1 Functional Relationships(s)
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1 Sensitivity and mathematical analysis demonstrate the importance of the two rate limiting enzymes 3-hydroxy-3-methylglutaryl-CoA reductase and squalene synthase in controlling the concentration of substrates within the pathway as well as that of cholesterol. Cholesterol farnesyl-diphosphate farnesyltransferase 1 Homo sapiens