Title : Active-site solvent replenishment observed during human carbonic anhydrase II catalysis.

Pub. Date : 2018 Jan 1

PMID : 29354275






2 Functional Relationships(s)
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1 The structures reveal new intermediate solvent states of hCA II that provide crystallographic snapshots during the restoration of the proton-transfer water network in the active site. Water carbonic anhydrase 2 Homo sapiens
2 This study provides the first "physical" glimpse of how a water reservoir flows into the hCA II active site during its catalytic activity. Water carbonic anhydrase 2 Homo sapiens