Title : Effects of Quercetin, Kaempferol, and Exogenous Glutathione on Phospho- and Total-AKT in 3T3-L1 Preadipocytes.

Pub. Date : 2018 Nov 2

PMID : 29345961






3 Functional Relationships(s)
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1 The aim of this study was to investigate the effects of two flavonoids, quercetin and kaempferol, and exogenous glutathione (GSH) on the expressions of phospho- and total-AKT levels in 3T3-L1 preadipocytes. Quercetin thymoma viral proto-oncogene 1 Mus musculus
2 However, significant (p <.05) decreases in phospho-AKT levels in cells treated with quercetin, kaempferol, and GSH at certain doses were observed compared to their respective controls. Quercetin thymoma viral proto-oncogene 1 Mus musculus
3 Findings suggest that exposure of 3T3-L1 preadipocytes to quercetin, kaempferol, and GSH may block the activation of AKT, suggesting the role such compounds play in cell differentiation in 3T3-L1 cells. Quercetin thymoma viral proto-oncogene 1 Mus musculus