Title : High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.

Pub. Date : 2018 Oct

PMID : 29334602






1 Functional Relationships(s)
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1 The combination of TMZ and metformin enhanced AMPK phosphorylation and inhibited mammalian target of rapamycin phosphorylation, AKT phosphorylation, and p53 expression. Temozolomide tumor protein p53 Homo sapiens