Title : Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells.

Pub. Date : 2018 Mar

PMID : 29326072






1 Functional Relationships(s)
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1 Western blot results indicated that BSNQ and OSNQ up-regulated the phosphorylation of p38 and JNK, and down-regulated the phosphorylation of ERK, Akt and STAT3, and that these effects were blocked by N-acetyl-l-cysteine. Acetylcysteine AKT serine/threonine kinase 1 Homo sapiens