Title : The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma.

Pub. Date : 2018 Jan 5

PMID : 29305580






3 Functional Relationships(s)
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1 The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma. Sorafenib microRNA 494 Homo sapiens
2 MiR-494 overexpression increased sorafenib resistance via mTOR pathway activation in HCC cell lines and, in line, high miR-494 levels associated with decreased sorafenib response in two HCC animal models. Sorafenib microRNA 494 Homo sapiens
3 MiR-494 overexpression increased sorafenib resistance via mTOR pathway activation in HCC cell lines and, in line, high miR-494 levels associated with decreased sorafenib response in two HCC animal models. Sorafenib microRNA 494 Homo sapiens