Title : Is ABCA1 a lipid transfer protein?

Pub. Date : 2018 May

PMID : 29305383






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ABCA1 functions as a lipid transporter because it mediates the transfer of cellular phospholipid (PL) and free (unesterified) cholesterol (FC) to apoA-I and related proteins present in the extracellular medium. Phospholipids apolipoprotein A1 Homo sapiens
2 ABCA1 functions as a lipid transporter because it mediates the transfer of cellular phospholipid (PL) and free (unesterified) cholesterol (FC) to apoA-I and related proteins present in the extracellular medium. Phospholipids apolipoprotein A1 Homo sapiens
3 The amphipathic alpha-helices in apoA-I confer detergent-like properties on the protein enabling it to solubilize PL and FC in these membrane domains to create a heterogeneous population of discoidal nascent HDL particles. Phospholipids apolipoprotein A1 Homo sapiens