Title : Tumor targeted delivery of doxorubicin in malignant peripheral nerve sheath tumors.

Pub. Date : 2018

PMID : 29304038






3 Functional Relationships(s)
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1 IL13 conjugated liposomal doxorubicin was formulated and shown to bind and internalized in the MPNST cell culture model demonstrating cytotoxic effect. Doxorubicin interleukin 13 Mus musculus
2 Our subsequent in vivo investigation in the STS26T MPNST sciatic nerve tumor model indicated that IL13 conjugated liposomal doxorubicin (IL13LIPDXR) was more effective in inhibiting tumor progression compared to unconjugated liposomal doxorubicin (LIPDXR). Doxorubicin interleukin 13 Mus musculus
3 Our subsequent in vivo investigation in the STS26T MPNST sciatic nerve tumor model indicated that IL13 conjugated liposomal doxorubicin (IL13LIPDXR) was more effective in inhibiting tumor progression compared to unconjugated liposomal doxorubicin (LIPDXR). Doxorubicin interleukin 13 Mus musculus